In particular, if you are training too much, too quickly, the muscles will remind you of the fact. Fail to rest adequately and overuse muscles you haven't used for a while, and you are heading for injury.
This article confirms this but offers advice on what to do should the worst happen, and you are injured.
In this article, tight calves are discussed.
Have I got tight calf muscles?https://www.sportsinjuryclinic.net/sport-injuries/lower-leg/calf-pain/tight-calf-muscles
The signs of tight calf muscles that the athlete might feel is a gradual tightening of the calf muscles over time, which can get worse when running or improve while running only to tighten up later. Palpating (feeling) the muscles may identify tight lumps bumps and areas of spasm where the muscle fibres have tightened up and will be painful and tender to touch.